Central Vein Stenosis Due to Dialysis Catheter Insertion in Subclavian Compared to Jugular Vein

Launched by SKANE UNIVERSITY HOSPITAL · May 1, 2021

Keywords

ClinConnect Summary

This clinical trial is studying the effects of placing temporary hemodialysis catheters (tHDC) in two different veins: the subclavian vein and the jugular vein. The goal is to understand which location might lead to fewer complications, especially a condition called central vein stenosis (CVS), which can happen when catheters are inserted. While the subclavian vein has some advantages, like a lower risk of infections and being more comfortable, there are concerns that it may cause CVS more often than the jugular vein. The researchers are looking to see if using ultrasound guidance during the catheter insertion can help reduce tissue damage and complications.

To participate in the trial, you need to be an adult aged 18 or older who requires a temporary catheter for at least seven days. You should be able to give informed consent and not have certain conditions like existing vein blockages or specific heart devices. If you join the study, you can expect careful monitoring and support from the medical team throughout the process. The researchers hope this study will help improve the safety and comfort of catheter placements for patients in need of dialysis.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adults (18 years of age or older).
• • In need of a tCDC with an expected treatment time of at least 7 days.
• • Informed consent.
• Exclusion Criteria:
• • Intravenous pacemaker or a PICC-line via right-sided central veins in situ.
• • Known right-sided CVS.
• • AV fistula on the right upper extremity.
• • History of central venous vascular interventions including stents, dilatations and more (but not previous central venous catheterization).
• • Central venous catheter in the right internal jugular vein or in the right subclavian vein in situ.
• • Either the right jugular vein or the right subclavian vein unavailable for catheterization due to, e.g., local skin infection, thrombosis or inability to visualize the vein with ultrasound.
• • Known allergy to iodinated contrast agents.
• • BMI \>35 kg/m2.
• • No study physician available for the catheterization.