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Search / Trial NCT04875936

Neurofeedback Intervention for Reading Deficits in Subacute Stroke

Launched by KESSLER FOUNDATION · May 3, 2021

Trial Information

Current as of July 01, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is looking at a new way to help people who have trouble reading after having a stroke. The study aims to improve reading skills by using a special technique called real-time functional magnetic resonance imaging (fMRI) neurofeedback. This method allows stroke patients to see and control their own brain activity while they practice reading. By focusing on the areas of the brain responsible for language, researchers hope to help participants regain better reading abilities.

To participate in this trial, individuals must be between 18 and 80 years old and have experienced their first stroke on the left side of the brain within the last three months. They should also have had good reading skills before the stroke. Unfortunately, those who cannot undergo an MRI scan or have had other neurological conditions may not be eligible. Participants will engage in activities that help them learn how to activate the brain areas needed for reading, and they'll receive support throughout the process. This innovative approach could offer new hope for improving reading skills after a stroke.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • First-ever left-hemisphere stroke \< 3 months prior to study recruitment or healthy volunteer
  • Age: 18 - 80 years old
  • Fluent and literate in English prior to stroke
  • Reading deficits, defined as \>3 errors on the Paragraphs test (subtests VIII, IX) of the Reading Comprehension Battery for Aphasia-2nd ed. (RCBA-2) in keeping with the healthy control accuracy criterion of 86-100% correct.
  • Exclusion Criteria:
  • Inability to consent or complete study tasks
  • Inability to undergo MRI (e.g., pregnancy, non-MRI compatible implants, claustrophobia)
  • A history of prior neurological disease (e.g., brain tumor, Alzheimer's disease)

About Kessler Foundation

Kessler Foundation is a leading nonprofit organization dedicated to advanced rehabilitation research and the development of innovative strategies to improve the lives of individuals with disabilities. With a strong emphasis on clinical trials and evidence-based practices, the Foundation collaborates with academic institutions, healthcare providers, and industry partners to explore novel therapeutic approaches and technologies. Its commitment to enhancing mobility, cognitive function, and overall quality of life for people with neurological and musculoskeletal conditions drives its mission to transform rehabilitation outcomes through cutting-edge research and community engagement.

Locations

West Orange, New Jersey, United States

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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