Dynamics of Markers of Infection and Inflammation in Hospitalized Coronavirus Disease 2019 (COVID-19) Patients

Launched by UNIVERSITY HOSPITAL HRADEC KRALOVE · May 10, 2021

Keywords

ClinConnect Summary

This clinical trial is studying how different patients with COVID-19 respond to the infection, especially those who are hospitalized with moderate to severe cases. Researchers want to understand how the body’s inflammatory markers, which can indicate the severity of the infection, change over time and how patient characteristics, like existing health conditions or treatments they receive, affect these responses. By observing these changes in hospitalized patients, the study aims to gather important information that could help improve care for future COVID-19 patients.

If you're considering participating in this trial, you may be eligible if you've tested positive for COVID-19 within the last two weeks and have specific lung issues shown on imaging tests, along with needing oxygen support to keep your blood oxygen levels stable. Participants can expect to have their health closely monitored throughout their hospital stay, allowing researchers to collect valuable data. It's important to note that individuals with certain lung diseases or heart failure cannot participate in this study.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • SARS CoV2 positive test within last 14 day
• • bilateral infiltrates on chest X.ray or CT
• • need for oxygen to keep pulse oximetry saturation above 92% or other respiratory support measures (HFNO, non-invasive ventilation or invasive ventilation)
• Exclusion Criteria:
• • known history of intersticial lung disease
• • known history of congestive heart failure