Opioid Free Anesthesia-Analgesia Strategy and Surgical Stress in Elective Open Abdominal Aortic Aneurysm Repair

Launched by UNIVERSITY OF CRETE · May 16, 2021

Keywords

ClinConnect Summary

This clinical trial is exploring a new approach to anesthesia for patients undergoing elective open surgery to repair an abdominal aortic aneurysm, which is a serious condition affecting the blood vessels. The trial aims to see if using an opioid-free anesthesia strategy can reduce the body’s stress response to surgery and improve recovery outcomes compared to traditional methods that use opioids. Participants in this study will receive a combination of different medications that work in various ways to manage pain and reduce inflammation during and after the surgery.

To be eligible for this trial, participants should be between 40 and 85 years old, and they must be scheduled for elective surgery to repair an abdominal aortic aneurysm. However, individuals with certain health conditions, such as active infections, cancer, or those who are immunocompromised, cannot participate. If you decide to take part in this study, you can expect to receive careful monitoring and support throughout the surgical process, with the hope of experiencing less pain and a quicker recovery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patient Consent
• • 2. Age between 40 and 85 years old
• • 3. Patients undergoing Elective Open Abdominal Aortic Infrarenal Aneurysm Repair
• Exclusion Criteria:
• • 1. Immunocompromised patients
• • 2. Patients with active infection
• • 3. Reoperation on the aorta
• • 4. Inflammatory bowel Disease
• • 5. Malignancy
• • 6. Chronic Inflammatory conditions (e.g. Rheymatoid arthritis, Psoriatic arthritis)
• • 7. Chronic corticosteroid or immunosuppressive drug use
• • 8. Intraoperative transfusion with \>2 units of packed Red Blood Cells