Intra-sheath vs Extra-sheath Injection for De Quervain's Tenosynovitis
Launched by UNIVERSITY OF CALIFORNIA, DAVIS · May 18, 2021
Trial Information
Current as of July 05, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is investigating two different methods of delivering steroid injections for a condition called De Quervain's Tenosynovitis, which causes pain in the wrist and thumb. The study aims to find out if injecting the steroid directly into the sheath around the affected tendon (intra-sheath) is more effective than injecting it outside of that sheath (extra-sheath). Participants will be divided into two groups, and their pain levels will be measured before and six weeks after the injection to see which method works better.
To participate in this trial, individuals need to be between the ages of 65 and 74, have a confirmed diagnosis of De Quervain's, and report a certain level of pain. They should not have had prior steroid injections or surgeries for this condition and must not have certain health issues or allergies related to the medications used in the trial. If eligible, participants can expect a thorough evaluation of their pain and follow-up assessments to determine how well the treatment has worked. This study is currently recruiting participants, and those who join will help provide valuable information on the best treatment options for this common hand condition.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Signed informed consent from the patient exclusively and not a legal representative
- • Clinically diagnosed with De Quervain's
- • VAS score of at least 40mm pre-injection
- • Life expectancy greater than 1 year
- Exclusion Criteria:
- • Having previously undergone steroid injection in the treatment of De Quervain's
- • Having previously undergone surgery for De Quervain's in the affected wrist
- • Having previously undergone steroid injection and failed in the treatment of trigger finger
- • Allergies to lidocaine or dexamethasone
- • Underlying serious medical conditions that would place the patient at risk
- • Past history of hypothyroidism or rheumatoid arthritis
- • Pregnant women
- • Prisoners
About University Of California, Davis
The University of California, Davis (UC Davis) is a leading research institution renowned for its commitment to advancing healthcare through innovative clinical trials and studies. With a strong focus on interdisciplinary collaboration, UC Davis leverages its extensive expertise in medical research, education, and patient care to drive breakthroughs in various fields, including medicine, public health, and agriculture. The university's clinical trial programs emphasize rigorous scientific methodology and ethical standards, aiming to translate research findings into impactful treatments and improved patient outcomes. Through its state-of-the-art facilities and a dedicated team of researchers and healthcare professionals, UC Davis is at the forefront of transforming healthcare practices and addressing critical health challenges.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Sacramento, California, United States
Patients applied
Trial Officials
Christopher O Bayne, MD
Principal Investigator
University of California, Davis
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Similar Trials