A Time-lapse Monitoring Prospective Study

Launched by ART FERTILITY CLINICS LLC · May 20, 2021

Keywords

ClinConnect Summary

The use of extended embryo culture to the blastocyst stage and PGT-A has enabled identification and selection of embryos with the best developmental potential and improved IVF clinical outcomes. It is considered a routine practice to grade the embryos on day 3 of development, which will require disturbing the culture conditions by annotating the embryos using inverted microscopes. However, the application of Time-lapse technology (TLS) allows annotating the embryos on day 3 without interrupting the culture conditions, especially if TLS is combined with single-step culture medium.

There are...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Patients with a minimum of 8 - 10 follicles during ovarian stimulation
• • Patients with a minimum of 8 mature oocytes
• • PGT-A
• • ICSI
• • BMI\<35
• • Age 18- 40
• • Fresh or frozen ejaculatory sperm \>10,000 motile sperm
• • Any Ovarian stimulation
• • Embryos cultured in Time-lapse system
• Exclusion Criteria:
• • PGT-M or PGT-SR
• • Previous history of embryo arrest
• • Endometriosis
• • Hydrosalpinx
• • History of uterine abnormality or previous uterine surgery
• • History of previous treatment which may impact the ovarian reserve (adnexal surgery, chemotherapy, radiation...)