Pragmatic Trial Comparing Weight Gain in Children With Autism Taking Risperidone Versus Aripiprazole

Launched by VANDERBILT UNIVERSITY MEDICAL CENTER · May 21, 2021

Keywords

ClinConnect Summary

This clinical trial is studying two medications, risperidone and aripiprazole, which are used to help manage behavior problems in children with autism. The main goal of the study is to find out which medication might cause more weight gain in these children. The trial is being conducted in a real-world setting, meaning that it will take place in a clinical environment where children are regularly seen for their autism treatment.

To participate, children must be 17 years old or younger, have a diagnosis of autism, and be experiencing behavioral issues. They should also be new to these types of medications. Unfortunately, children who are 18 and older or have previously taken similar medications will not be eligible. If your child meets these criteria, they can expect to be part of a study that aims to improve understanding of how these medications affect weight gain. This information could be really helpful for families and doctors when choosing the right treatment for children with autism.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • age 17 years and younger
• • diagnosed with autism
• • have behavior problems
• • seen in Vanderbilt clinic
• • naïve to atypical antipsychotics
• Exclusion Criteria:
• • 18 years or older
• • history of atypical antipsychotic use
• • not diagnosed with autism