Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 3

Launched by VIRGINIA COMMONWEALTH UNIVERSITY · Jun 4, 2021

Keywords

ClinConnect Summary

This clinical trial is looking at how different types of exercise training can affect blood vessel health in people with mental health conditions, specifically those experiencing posttraumatic stress disorder (PTSD) or generalized anxiety disorder (GAD). The researchers want to see if exercise can help improve blood flow and overall vascular function in both healthy individuals and those with these mental health challenges.

To participate, individuals aged 65-74 who are generally healthy and free from serious heart, lung, or metabolic diseases can apply. Those with PTSD need a specific score on a questionnaire designed to measure their symptoms, while individuals with GAD must meet certain criteria related to their anxiety levels. Participants will not be eligible if they are on certain medications, are current smokers, or have other specific health issues. If selected, participants can expect to engage in various exercise programs and contribute to important research that could help improve health outcomes for people with mental health disorders.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • apparently healthy and free of overt cardiovascular, pulmonary, or metabolic disease
• • for PTSD group, a score of ≥ 33 on PCL-5 checklist
• • for GAD group, a score of ≥ 10 on the GAD-7 self-report scale and \< 33 on the PCL-5 checklist
• • for Healthy Control group, a score of ≤ 10 on the GAD-7 self-report scale and \< 33 on the PCL-5 checklist
• Exclusion Criteria:
• • taking medications that could influence cardiovascular function
• • current smokers who have recently quit smoking
• • illicit drug use or excessive alcohol consumption
• • pregnant women
• • significant calorie restriction or vitamin/mineral deficiencies
• • limited English proficiency