ClinConnect ClinConnect Logo
Search / Trial NCT04917562

Refractive Transepithelial Photo-keratectomy (T-PKR) in High Myopia

Launched by CENTRE HOSPITALIER RÉGIONAL METZ-THIONVILLE · Jun 1, 2021

Trial Information

Current as of August 15, 2025

Completed

Keywords

Transepithelial Photorefractive Keratectomy High Myopia Mitomycin C Corneal Haze Efficacy Predictibility

ClinConnect Summary

In this retrospective study, 69 high myopic eyes of 6 diopters or more were treated in 38 patients by Trans-PRK with the SCHWIND Amaris 500E® excimer laser platform without the use of mitomycin-C. Several outcomes are measured in treated patients, such as postoperative uncorrected visual acuity (UCVA), best spectacle corrected visual acuity (BSCVA), efficacy, safety and predictability of the procedure, as well as corneal haze measurement. The patients are followed-up for 3 months.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • age ≥18 years,
  • myopic sphere of -6 diopters or more,
  • astigmatism less than 3 diopters,
  • stable myopia not progressing for more than one year
  • Exclusion Criteria:
  • age \<18 years,
  • myopic sphere less than -6 diopters,
  • astigmatism greater than 3 diopters,
  • progressive myopia (variation of more than 0.5 diopters over one year),
  • abnormal corneal topography or the presence of manifest keratoconus,
  • pre-existing eye pathology,
  • history of eye surgery,
  • active inflammatory or infectious eye disease,
  • dermatological disease or systemic connectivitis

About Centre Hospitalier Régional Metz Thionville

The Centre Hospitalier Régional Metz-Thionville is a leading healthcare institution in the Grand Est region of France, dedicated to delivering high-quality medical care and advancing clinical research. With a multidisciplinary team of experienced healthcare professionals, the center emphasizes patient-centered services and innovative treatment approaches. Committed to enhancing medical knowledge and improving patient outcomes, the hospital actively participates in clinical trials across various therapeutic areas, fostering collaboration with academic institutions and industry partners to drive advancements in healthcare.

Locations

Metz, , France

Patients applied

0 patients applied

Trial Officials

Jean Marc PERONE, MD

Principal Investigator

CHR Metz Thionville Hopital de Mercy

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Similar Trials