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Search / Trial NCT04928495

Clinical Trial With N-acetylcysteine and Bromhexine for COVID-19

Launched by UNIVERSIDADE FEDERAL DO CEARA · Jun 15, 2021

Trial Information

Current as of August 11, 2025

Unknown status

Keywords

N Acetylcysteine Bromhexine Covid 19 Clinical Trial

ClinConnect Summary

Several therapeutic agents have been evaluated for the treatment of COVID-19, but only one, the antiviral drug called remdesivir administered intravenously, has shown to be effective in shortening the duration of the disease by 26.7% in critically ill patients. This proposal has the primary objective (1) to determine the effect of N-acetylcysteine (NAC; reducing substance and complementary viral intercepting action) and combination of NAC + bromhexine (BMX; viral protease inhibitor), on the clinical duration of COVID-19 evaluated on the 7th. day of outpatient follow-up, observing the score ...

Gender

ALL

Eligibility criteria

  • The inclusion criteria will be:
  • 1. patients with clinical signs and symptoms of COVID-19; and
  • 2. patients over 18 years and below 60 years of age.
  • The exclusion criteria will be:
  • 1. participate in another clinical intervention study;
  • 2. you have a disease or other medical condition that prevents you from using the medications for this intervention;
  • 3. patient incapable of ingesting, retaining and absorbing the intervention medications; and (d) is mentally disabled.

About Universidade Federal Do Ceara

The Universidade Federal do Ceará (UFC) is a prestigious public research university located in Brazil, renowned for its commitment to advancing knowledge and innovation in various fields, including healthcare and clinical research. With a strong focus on interdisciplinary collaboration, UFC actively engages in clinical trials to evaluate new therapies and healthcare interventions, aiming to improve patient outcomes and contribute to the global medical community. The university's dedicated research teams leverage state-of-the-art facilities and ethical practices to ensure the integrity and success of their clinical studies, making significant strides in the fields of medicine and public health.

Locations

Fortaleza, Ceará, Brazil

Fortaleza, , Brazil

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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