Screening and Application Research of Early Diabetic Nephropathy Markers Based on Lipidomics.

Launched by SECOND AFFILIATED HOSPITAL, SCHOOL OF MEDICINE, ZHEJIANG UNIVERSITY · Jun 14, 2021

Keywords

ClinConnect Summary

This clinical trial is studying early markers of diabetic nephropathy (DN), a serious kidney problem that can occur in people with diabetes. The goal is to find new ways to detect this condition earlier and more accurately than current methods, which mainly rely on testing for protein in the urine and kidney function. By analyzing certain fats (lipids) in the body, researchers hope to identify new markers that could help doctors recognize kidney damage sooner, potentially reducing the risk of severe kidney issues by up to 50%.

To participate in this study, you need to be between 20 and 80 years old, and you should be willing to follow the study's guidelines for more than five years. You also need to have signed an informed consent form agreeing to participate. However, if you have certain other kidney diseases, active infections, or specific conditions that affect your health, you may not be eligible. If you join the trial, you will help researchers learn more about how to better diagnose and treat kidney problems related to diabetes, which could lead to better health outcomes for many people.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Subjects who have signed informed consent.
• • 2. Subjects were 20-80 years old and of either gender.
• • 3. Subjects showed good compliance, and the follow-up data was available for \>5 years.
• Exclusion Criteria:
• • 1. Meet the 1999 World Health Organization (WHO) diagnostic criteria for T1DM、T2DM;
• • 2. Renal diseases caused by other causes, including primary and secondary;
• • 3. All kinds of acute infections;
• • 4. The expected life expectancy (life expectancy or related diseases) was less than 5 years according to the researcher's judgment.
• • 5. Drug users or drug abusers;
• • 6. Sexually transmitted diseases such as viral hepatitis, AIDS and syphilis, and infectious diseases such as tuberculosis are in an active period;
• • 7. Any situation judged by the researcher that affects enrollment.