Outcomes After Dorsal Wrist Ganglia Excision With or Without PIN

Launched by KENNETH TAYLOR, M.D. · Jun 17, 2021

Keywords

ClinConnect Summary

This study is testing whether adding a small nerve procedure to the usual surgery for a dorsal wrist ganglion cyst helps people feel less pain and move their wrist better. Participants are randomly assigned to one of two options: remove the cyst alone, or remove the cyst plus a partial denervation of a wrist nerve (PIN). The researchers hope that the extra nerve procedure may improve pain, daily function, and overall wrist ability after surgery. The study uses a double-blind design, meaning neither the patient nor the examiner who tests the wrist knows which surgery was done.

Eligible participants are adults 18 and older with a painful, limiting dorsal wrist ganglion cyst who have chosen to have surgery and can complete forms in English. Exclusions include minors, non-elective surgeries, prior wrist surgery or instability, neurological problems in the wrist, pregnancy, cognitive issues, or imprisonment. Participants will complete four questionnaires about pain and function before surgery and at several points up to one year after, and will have physical tests of strength and wrist movement at 2 weeks, 12 weeks, and 6 months. The trial is being conducted at Penn State Health campuses in Camp Hill and Hershey, Pennsylvania, and is currently enrolling with an estimated completion in late 2028.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Greater than or equal to 18 years of age
• • Gender: male/female (non-pregnant)
• • Diagnosis of symptomatic (pain and limited ability to perform activities of daily living) dorsal wrist ganglion cyst
• • Subjects who have chosen surgical management for their ganglion cyst diagnosis
• • Fluent in written and spoken English
• • Subject is able to provide voluntary, written informed consent
• • Subject, in the opinion of the clinical investigator, is able to understand the clinical investigation and is willing to perform all study procedures and follow-up visits
• • Non-Prisoners
• Exclusion Criteria:
• • Less than 18 years of age
• • Non-elective surgery for this diagnosis
• • Chronic wrist instability of the operative extremity
• • Comorbid neurologic maladies of the operative extremity
• • Prior wrist surgery on either extremity
• • Non-English speaking
• • Prisoners
• • Pregnancy
• • Cognitive Impairment