Aligning Medications With What Matters Most
Launched by JOHNS HOPKINS UNIVERSITY · Jun 22, 2021
Trial Information
Current as of October 19, 2025
Completed
Keywords
ClinConnect Summary
People living with dementia (PLWD) use more medications and have more complex medication regimens than people without dementia. Medication regimen complexity is a major source of burden for family caregivers of PLWD and has been associated with numerous adverse outcomes. Therefore, the investigators propose a novel intervention, ALIGN: Aligning Medications with What Matters Most, to optimize prescribing and reduce medication regimen complexity by focusing on what matters most to the patient and caregiver, beyond rigid adherence to clinical practice guidelines. ALIGN is informed by learnings...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age 65 or greater
- • Diagnosis of dementia from International Classification of Diseases (ICD) -9 or ICD-10 codes
- • At least one other chronic condition
- • Five or more chronic medications (to include all prescription and over-the-counter medications, both scheduled and as needed)
- • Have a primary care physician at the pilot clinic who has enrolled in the study; this will be defined as having had at least 1 previous visit with that physician
- Care partners:
- • - Family or other companions age 21 years or greater who regularly help the patient with managing medications
- Exclusion Criteria:
- • As both the pilot and the planned pragmatic trial will be based in primary care, individuals residing in long term care facilities or enrolled in hospice will be excluded.
- • Individuals who cannot converse comfortably in English will be excluded because the FCMAHS has not been validated in other languages.
About Johns Hopkins University
Johns Hopkins University, a prestigious research institution located in Baltimore, Maryland, is renowned for its commitment to advancing medical science and public health through innovative clinical trials. With a rich history of groundbreaking research and a multidisciplinary approach, the university's clinical trial initiatives focus on translating scientific discoveries into effective treatments and interventions. Leveraging state-of-the-art facilities and a collaborative network of experts, Johns Hopkins University conducts rigorous clinical studies that aim to improve patient outcomes and address critical health challenges. Its dedication to ethical standards and participant safety underscores its role as a leader in clinical research.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Baltimore, Maryland, United States
Aurora, Colorado, United States
Patients applied
Trial Officials
Ariel Green, MD, MPH, PhD
Principal Investigator
Johns Hopkins University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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