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Search / Trial NCT04947163

Effects of Inspiratory Muscle Training (IMT) on Balance Ability and Quality of Life of Diabetes Mellitus Patients

Launched by RIPHAH INTERNATIONAL UNIVERSITY · Jun 30, 2021

Trial Information

Current as of August 19, 2025

Completed

Keywords

Balance Diabetes Mellitus Inspiratory Muscle Training Quality Of Life

ClinConnect Summary

Diabetes Mellitus (DM) is a chronic metabolic disease characterized by hyperglycemia due to either deficiency of insulin or the inability of the body to utilize it. Hyperglycemia ultimately leads to multiple organ damage in patients with uncontrolled diabetes. The incidence occurs mostly at the age of 55 years equally affecting both genders. The prevalence of diabetes has been increased four times in the last three decades worldwide and global prevalence is increasing alarmingly with about 1 out of every 11 individuals having diabetes mellitus with 90% patients having type 2 diabetes mellit...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Mini Mental State Examination (MMSE) score \>24
  • Type II diabetes: Post 5-8 years diagnosis
  • Berg Balance score (30-40)
  • Presence of polyneuropathy confirmed through Modified Toronto Clinical Scoring System.
  • Exclusion Criteria:
  • Patients on oxygen therapy
  • Uncontrolled diabetes (Confirmed through HbA1C) or disease exacerbation in last 3 months.
  • Patients practicing regular physical activity, any balance training in the last 6 months and previous or current experience with IMT
  • Patients with musculoskeletal comorbidities that may impair exercise performance
  • Peripheral oxygen saturation (SpO2) \< 90% during the Six-Minute Walk Test (6MWT)
  • Patients with long COVID syndrome
  • Hypertensive subjects without control medication as well as those presenting with a hypertensive peak (\> 140/90 mmHg) for more than 3 consecutive days
  • Patients with cardiorespiratory diseases or patients taking drugs that effect balance e.g., beta blockers, anti-anxiety and anti-depressant drugs.

About Riphah International University

Riphah International University is a leading educational institution based in Pakistan, dedicated to advancing healthcare and medical research through innovative clinical trials. With a commitment to excellence in research and education, Riphah emphasizes ethical standards and scientific integrity in its clinical studies. The university collaborates with various stakeholders, including healthcare professionals and industry partners, to enhance patient outcomes and contribute to the global body of medical knowledge. Through its robust research programs, Riphah International University aims to foster a culture of inquiry and improve healthcare delivery both locally and internationally.

Locations

Rawalpindi, Punjab, Pakistan

Patients applied

0 patients applied

Trial Officials

Arshad Nawaz Malik, PhD

Principal Investigator

Riphah International University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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