Intraoperative Neuromonitoring of Pelvic Autonomous Nerve Plexus During Total Mesorectal Excision

Launched by LARISSA UNIVERSITY HOSPITAL · Jun 30, 2021

Keywords

ClinConnect Summary

This clinical trial is investigating a technique called intraoperative neuromonitoring (pIONM) during a specific surgery known as Total Mesorectal Excision (TME) for patients with rectal cancer. The main goal of the study is to see if using this method can help improve bowel and urinary function after surgery, as well as enhance the overall quality of life for patients recovering from this procedure.

To participate in the trial, individuals should be between the ages of 18 and 90 and must have a confirmed diagnosis of rectal cancer that requires surgical removal through TME. Participants need to be able to provide consent and should not have certain medical conditions, such as infections or the presence of a pacemaker. Those who join the study can expect close monitoring during and after their surgery, with a focus on how well their bowel and urinary functions recover. This trial is currently recruiting participants, and by taking part, individuals can contribute to valuable research that may improve future treatments for rectal cancer.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Histologically confirmed rectal cancer
• • Surgical resection with TME
• • \<90 years old
• • Signed informed consent
• Exclusion Criteria:
• • Emergency operation
• • Presence of pacemaker
• • Partial mesorectal excision
• • Sepsis or systematic infection
• • Physical or mental impairment
• • Pregnancy or nursing
• • Insufficient preoperative data for the urogenital/ anorectal function
• • Lack of compliance with the research process