Semantic Rehabilitation for Patients With Primary Progressive Semantic Aphasia

Launched by UNIVERSITY HOSPITAL, TOULOUSE · Jun 30, 2021

Keywords

ClinConnect Summary

This clinical trial is looking at a new treatment approach called semantic rehabilitation for people with primary progressive semantic aphasia, a condition that affects language and communication skills. The goal is to see how well this therapy works for patients who are experiencing mild to moderate dementia. If you or a loved one is between the ages of 18 and 74, speaks French, and has been diagnosed with this specific type of aphasia, you might be eligible to participate in the study.

Participants in the trial will receive the semantic rehabilitation treatment and will help researchers understand its effectiveness. However, there are certain criteria that could prevent someone from taking part, such as serious vision or hearing problems, past brain injuries, or untreated mental health issues. If you think this study might be a good fit for you or someone you know, it could be a valuable opportunity to contribute to research that aims to improve communication for those affected by this condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Have a diagnosis of primary progressive semantic aphasia according to the criteria of Gorno-Tempini et al (2011) (Appendix A)
• • Being in the mild to moderate stage of dementia (MMSE score between 10 and 28) (Crum et al., 1993; Derouesné et al., 1999)
• • Common French
• • Being affiliated to a social security scheme
• • Being over the age of 18 years old
• Exclusion Criteria:
• • Have significant uncorrected visual and/or hearing impairment
• • Have a history of brain injuries, major head trauma
• • Have untreated psychiatric disorders
• • Have significant motor and/or comprehension problems that make it impossible to take part in the study
• • Chronical use of drugs and/or alcohol
• • Under guardians or curators
• • Severe depression (Beck's depression scale score \> 9) (Beck \& al., 1961)