ClinConnect ClinConnect Logo
Search / Trial NCT04959097

RB Liquid Biopsy Biorepository

Launched by CHILDREN'S HOSPITAL LOS ANGELES · Jul 1, 2021

Trial Information

Current as of June 27, 2025

Recruiting

Keywords

Retinoblastoma Rb Ocular Oncology Aqueous Humor

ClinConnect Summary

The RB Liquid Biopsy Biorepository trial is researching a new way to better understand retinoblastoma (RB), a type of eye cancer that mainly affects young children. Instead of waiting until surgery to study the tumor, this study uses a sample of the aqueous humor, which is the clear fluid in the front part of the eye, to look for specific markers that can reveal important information about the cancer. This could help doctors diagnose and treat RB more effectively.

To participate in this trial, patients must be between the ages of 0 days and 18 years and have been diagnosed with either unilateral (one eye) or bilateral (both eyes) retinoblastoma at Children’s Hospital Los Angeles. Unfortunately, patients who are only seeking second opinions and have not been treated at this hospital are not eligible to join. If you or your child qualify, you can expect to provide a sample of the aqueous humor, which will be used to advance research on this condition and potentially improve future treatments for retinoblastoma.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • All patients, age 0 days to 18 years, with a diagnosis unilateral or bilateral retinoblastoma (RB) seen at CHLA (Children's Hospital Los Angeles).
  • Exclusion Criteria:
  • Patients referred for second opinions only and not treated at CHLA for any reason.

About Children's Hospital Los Angeles

Children's Hospital Los Angeles (CHLA) is a renowned pediatric healthcare institution dedicated to advancing the health and well-being of children through innovative research and clinical care. As a leading clinical trial sponsor, CHLA is committed to conducting high-quality, ethical research that addresses critical pediatric health issues. With a focus on translating scientific discoveries into effective treatments, CHLA collaborates with multidisciplinary teams and leverages state-of-the-art facilities to support a wide range of clinical trials. Their mission is to enhance the understanding and treatment of childhood diseases, ultimately improving outcomes for young patients and their families.

Locations

Los Angeles, California, United States

Patients applied

0 patients applied

Trial Officials

Jesse L Berry, MD

Principal Investigator

Children's Hospital Los Angeles

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Similar Trials