Cognitive Effects of Citicoline on Attention in Healthy Mean and Women

Launched by KIRIN HOLDINGS COMPANY, LIMITED · Jul 8, 2021

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a supplement called citicoline on how well healthy adults can pay attention and perform mental tasks. Researchers want to see if taking citicoline can help improve cognitive performance compared to a placebo, which is a non-active pill that looks the same but has no effects. The trial is currently looking for participants aged 18 to 35 who are in good health, have a normal weight, and agree to maintain their usual caffeine habits while eating breakfast daily during the study.

If you decide to participate, you'll take citicoline or a placebo and complete some questionnaires to measure your attention and cognitive performance. It's important to note that certain health conditions, like uncontrolled high blood pressure or recent hospitalizations for mental health issues, would make you ineligible for this trial. This study aims to gather information that could help understand how citicoline affects the brain and attention in healthy adults.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • male or female, 35-75 years of age
• • Scores ≥ 24 on the MMSE, ≤15 on the CESD-R, and scores below the population median (i.e., below 81.25, above 36.8) on the Gradual CPT
• • Self-reported poor attention
• • no health conditions that would prevent him or her from fulfilling the study requirements on the basis of medical history and routine laboratory test results
• • Understands the study procedures and signs forms providing informed consent to participate in the study and authorizes the release of relevant protected health information to the Principal Investigator.
• Exclusion Criteria:
• • color blindness
• • Known allergy or sensitivity to any of the ingredients in the study products and/or any ingredients of the breakfast meal provided
• • major medical or neurological illness
• • diagnosis of attention deficit hyperactive disorder (ADHD)
• • female who is pregnant, planning to be pregnant during the study period
• • requiring treatment with a drug which might obscure the action of the study treatment