Cohort of Premature Newborns for Charaterization of the Digestive Microbiota in Ulcerative Necrotizing Enterocolitis in Premature Infants

Launched by UNIVERSITY HOSPITAL, CLERMONT-FERRAND · Jul 12, 2021

Keywords

ClinConnect Summary

This clinical trial is studying the differences in gut bacteria between premature newborns who develop a serious condition called necrotizing enterocolitis (NEC) and those who do not. NEC is a condition that affects the intestines of premature babies, and researchers want to understand how the bacteria in their digestive systems might be involved. By comparing these two groups of babies while they are in the neonatal intensive care unit (NICU), the study aims to gather important information that could help improve treatment and outcomes for premature infants.

To be eligible for this study, babies must be born prematurely, meaning before 37 weeks of pregnancy, and must be receiving care at the designated hospital. Parents or guardians must also be able to give informed consent for their baby's participation. If you choose to participate, your baby will be monitored during their time in the NICU, and samples will be collected to study the gut bacteria. This research is important as it may lead to better understanding and management of NEC, ultimately helping to protect the health of future premature infants.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • born prematurely \< 37 weeks of amenorrhea at the maternity ward of the CHU
• • affiliated with a social security regime
• • the holders of parental authority are able to give an informed consent to participate in the research
• Exclusion Criteria:
• • fetal pathology
• • newborns whose holders of parental authority are under guardianship or under the age of 18
• • refusal of participation by holders of parental authority