Development of Effective, Opioid Sparing Techniques for Peri-operative Pain Management of Transgender Patients Undergoing Gender Affirming Surgeries
Launched by CEDARS-SINAI MEDICAL CENTER · Jul 16, 2021
Trial Information
Current as of June 27, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how to manage pain for transgender patients undergoing gender-affirming surgeries. Researchers want to find out which pain treatment options are most effective after surgery. The goal is to help patients experience less pain while using fewer opioids, which are strong pain medications that can have side effects and risks.
To participate in this trial, you need to be a transgender person aged 18 or older who is scheduled for specific surgeries performed by a group of qualified doctors. Participants will be closely monitored to see how well different pain management techniques work for them after their surgery. This study is important because it aims to improve care for transgender patients by identifying the best ways to manage pain during recovery. If you qualify and choose to participate, you will play a role in helping to enhance pain management strategies for others in the future.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Transgender persons 18 years and older
- • Undergoing gender affirming surgeries performed by either Dr. Maurice Garcia (orchiectomy only, vaginoplasty with or without canal \& orchiectomy, colon-vaginoplasty, \& peritoneal vaginoplasty; Stage I phalloplasty, or stage II phalloplasty); Dr. Edward Ray (feminizing chest surgery, masculinizing chest surgery, stage I phalloplasty); Dr. Amit Gupta (orchiectomy and peritoneal vaginoplasty only); or Dr. Yosef Nasseri (colon vaginoplasty surgery)
- Exclusion Criteria:
- • Patients who do not meet the inclusion criteria above
- • Any contraindications to the study drugs.
- • Patients with neurologic deficits that preclude them from sensing pain.
- • Patients with implanted pain neuromodulator devices (e.g., neurostimulator)
- • Patients who do not speak English
About Cedars Sinai Medical Center
Cedars-Sinai Medical Center is a renowned nonprofit academic medical center located in Los Angeles, California, recognized for its commitment to patient care, research, and education. As a leading institution in clinical trials, Cedars-Sinai harnesses innovative approaches to advance medical knowledge and improve treatment outcomes across various specialties. With a multidisciplinary team of experts, state-of-the-art facilities, and a patient-centered approach, Cedars-Sinai actively contributes to the development of novel therapies and interventions, ensuring the highest standards of clinical research while prioritizing patient safety and ethical considerations.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Los Angeles, California, United States
Patients applied
Trial Officials
Maurice M Garcia, M.D., MAS
Principal Investigator
Cedars-Sinai Medical Center
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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