Association of Apical Periodontitis With Hs-CRP and Hemogram Indices

Launched by POSTGRADUATE INSTITUTE OF DENTAL SCIENCES ROHTAK · Jul 19, 2021

Keywords

ClinConnect Summary

Prevalence of Apical periodontitis (AP) is reported in the range of 17% to 65% with higher prevalence reported in older patients. Infection of the pulp tissue of the affected tooth is the principal cause of apical periodontitis and it is characterised by inflammation of the periradicular tissues. Presentation of AP varies from classical signs of inflammation (pain, swelling, loss of function) to being completely asymptomatic with only signs of apical bone resorption on the radiograph. Histological changes seen in AP is localized infiltration of inflammatory cells and bone resorptions. AP ca...

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Eligibility criteria

• Inclusion Criteria:
• • Pulpal necrosis in mature mandibular molar as confirmed by negative response to pulp sensibility test (cold and electric pulp test)
• • Radiographic evidence of apical periodontitis in the form of periapical radiolucency
• • Radiographic alveolar bone breakdown not more than one third of root length.
• Exclusion Criteria:
• • Obese (BMI \>30 kg/m2), smoker, pregnant, diabetic, immunocompromised or have any other systemic inflammatory condition.
• • Having a positive history of antibiotic use within the past month or require antibiotic premedication for dental treatment (including infective endocarditis or prosthetic joint prophylaxis).
• • Teeth having previous root fillings, unrestorable teeth, fractured/perforated roots, grade 3 mobility, and history of recent periodontal therapy (within previous 6 months).
• • Teeth with established endodontic-periodontal lesions exhibiting \<2 mm radiopaque bone between the root apex.