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Search / Trial NCT04984304

Individualized Diagnosis and Treatment of Extraesophageal Reflux in Patients With Chronic Cough

Launched by UNIVERSITY HOSPITAL OSTRAVA · Jul 20, 2021

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Chronic Cough Extraesophageal Reflux Laryngopharyngeal Reflux Allergy Asthma

ClinConnect Summary

This clinical trial is studying the causes of chronic cough, which is a cough that lasts for three months or longer. One common reason for this type of cough is something called extraesophageal reflux (EER), where stomach contents go back up into the throat. The goal of the study is to accurately diagnose EER in patients who are experiencing chronic cough, whether or not they also have allergies.

If you are between the ages of 18 and 80 and have been dealing with a chronic cough, you might be eligible to participate. However, certain health conditions, like cancers in the head, neck, or lungs, as well as specific chronic lung diseases (except asthma), may prevent you from joining. Those who participate can expect to undergo tests to help identify if EER is contributing to their cough, and they will be helping researchers learn more about how to treat this condition effectively. If you're interested, this could be an important opportunity to find relief from your symptoms.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • age 18-80 years
  • patients with chronic cough (cough that lasts 3 months or longer)
  • consent with participation in the study
  • Exclusion Criteria:
  • patients using ACE inhibitors or Angiotensin II receptor blockers
  • patients with head and neck cancer
  • patients after radiotherapy in the head and neck area
  • patients with airway or lung cancer
  • patients with chronic lung disease except for bronchial asthma (COPD, interstitial lung disease, bronchiectasis, respiratory bronchiolitis)
  • patients with chronic rhinosinusitis

About University Hospital Ostrava

University Hospital Ostrava is a leading medical research institution located in Ostrava, Czech Republic, dedicated to advancing healthcare through innovative clinical trials and research initiatives. As a prominent sponsor of clinical studies, the hospital combines cutting-edge medical technology with a commitment to patient-centered care, fostering collaborations among multidisciplinary teams of healthcare professionals and researchers. With a focus on ethical standards and regulatory compliance, University Hospital Ostrava aims to contribute to the development of new therapies and improve treatment outcomes across various medical fields. Its robust research infrastructure and dedication to scientific excellence position it as a key player in the advancement of medical knowledge and patient care.

Locations

Ostrava, Moravian Silesian Region, Czechia

Patients applied

0 patients applied

Trial Officials

Viktória Hránková, MD,PhD,FESO

Principal Investigator

University Hospital Ostrava

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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