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Search / Trial NCT04986748

Using QPOP to Predict Treatment for Sarcomas and Melanomas

Launched by NATIONAL CANCER CENTRE, SINGAPORE · Jul 27, 2021

Trial Information

Current as of July 22, 2025

Recruiting

Keywords

Tumour Derived Models Organoids Ex Vivo Drug Testing Personalised Therapy Qpop

ClinConnect Summary

This clinical trial, called "Using QPOP to Predict Treatment for Sarcomas and Melanomas," is exploring how doctors can better predict which treatments will work best for patients with sarcoma or melanoma, two types of cancer. In this study, researchers will take samples of tumors from patients and create models that mimic the cancer. They will then test various drugs on these models to see how effective they are, which could help tailor treatments to individual patients in the future.

To be eligible for the trial, participants need to have a diagnosis of either sarcoma or melanoma and must have at least one tumor that can be biopsied or surgically removed. Patients will go through standard procedures for their cancer treatment, and their tumor samples will be used to create the models. The study is currently recruiting patients of all genders, aged between 76 and 159 years. It's important to know that by participating, patients may help advance cancer treatment options for others while also receiving standard care.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Diagnosis of sarcoma or melanoma
  • At least 1 tumour lesion amenable to fresh biopsy or resection
  • Signed informed consent from patient or legal representative
  • Able to comply with study-related procedures
  • Exclusion Criteria:
  • There are no specific exclusion criteria if patients meet the inclusion criteria

About National Cancer Centre, Singapore

The National Cancer Centre Singapore (NCCS) is a leading institution dedicated to cancer treatment, research, and education in Asia. As a premier clinical trial sponsor, NCCS focuses on advancing oncology through innovative therapies and comprehensive clinical studies. With a multidisciplinary team of experts and state-of-the-art facilities, the center is committed to improving patient outcomes and contributing to global cancer research initiatives. NCCS actively collaborates with various stakeholders, including academic institutions and pharmaceutical companies, to foster groundbreaking discoveries and enhance the understanding of cancer management and treatment.

Locations

Singapore, , Singapore

Patients applied

0 patients applied

Trial Officials

Valerie Shiwen Yang, BSc, MB BChir, PhD

Principal Investigator

National Cancer Centre, Singapore

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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