Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children

Launched by JOHNS HOPKINS UNIVERSITY · Jul 26, 2021

Keywords

ClinConnect Summary

This clinical trial is studying a new approach called the "PICU Up!" intervention, which aims to help critically ill children recover more effectively while they are in the Pediatric Intensive Care Unit (PICU). The focus is on encouraging early movement and activity for children who are on mechanical ventilation (a machine that helps them breathe) for at least 48 hours. This trial is important because many children who survive critical illnesses end up with long-lasting issues, and early mobility may help reduce these problems.

To participate in this study, children must be on mechanical ventilation for 48 hours by the third day of their PICU stay. However, those who are expected to have life support removed soon, have open surgeries, or are on certain life-saving machines are not eligible. If enrolled, participants will receive the PICU Up! intervention, which includes support for movement, managing sedation (medications that help with sleep), and preventing confusion, all tailored to their needs. This trial is taking place in several hospitals across the United States, and if successful, it could significantly improve care for children in critical condition and enhance their recovery outcomes.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Invasive mechanical ventilation via oral or nasal endotracheal tube ≥ 48 hours at 7 a.m. on PICU Day 3
• Exclusion Criteria:
• • Active or anticipated withdrawal of life support within 48 hours
• • Open chest or open abdomen
• • Current use of Extracorporeal Membrane Oxygenation (ECMO)