MASCOT Registry of Patients With Myeloproliferative Neoplasms Associated Splanchnic Vein Thrombosis

Launched by ROYAL FREE HOSPITAL NHS FOUNDATION TRUST · Jul 29, 2021

Keywords

ClinConnect Summary

Splanchnic or abdominal vein thrombosis (SVT) comprises thrombosis of hepatic, portal, superior mesenteric, splenic vein in isolation or combination. It has a prevalence of 1-2% in the general population based on autopsy reports. However, 40-50% of patients with hepatic vein thrombosis and about 25-30% of patients with PVT have an underlying myeloproliferative disease that is the cause of the thrombosis. Although some data on MPN-SVT have been published from European registries, the lack of sufficient clinical and scientific data in these patients has led to variation in treatment patterns ...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age\>18 years
• • Myeloproliferative neoplasm (MPN, WHO 2008, WHO 2016, BCSH) and splanchnic vein thrombosis
• • Isolated Jak2v617f allele and splanchnic vein thrombosis
• • MPN and portal cavernoma
• Exclusion Criteria:
• • -