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Search / Trial NCT04996342

A Cohort Study of Chronic Cardiovascular Diseases

Launched by PEKING UNIVERSITY FIRST HOSPITAL · Aug 2, 2021

Trial Information

Current as of July 22, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying patients with chronic cardiovascular diseases, such as high blood pressure that doesn't respond to treatment, heart disease, irregular heartbeats, and heart failure. The goal is to gather information about these patients' characteristics, their diagnosis and treatment plans, and how they do over the long term. By following these patients, the researchers aim to understand how different factors influence treatment choices and health outcomes.

To participate, patients must be diagnosed with one of the specific conditions listed, like coronary heart disease or pulmonary hypertension, and be willing to attend regular follow-up visits over time. The study is open to all adults aged 65 and older. Participants can expect to share their medical history and undergo regular check-ups, which will help doctors learn more about managing these diseases effectively. It's important to note that patients with severe health issues unrelated to their heart condition may not be eligible for the study.

Gender

ALL

Eligibility criteria

  • This study includes 9 disease-specific cohorts. The specific inclusion and exclusion criteria are as following:
  • 1. Refractory and secondary hypertension
  • Inclusion Criteria:
  • Patients diagnosed as refractory hypertension and/or secondary hypertension
  • Patients willing to accept long-term follow-up and regular return visits
  • Exclusion Criteria:
  • Severe diseases of other systems may affecting the life span of patients
  • 2. Coronary heart disease
  • Inclusion Criteria:
  • Patients undergoing coronary angiography and interventional therapy in the cath lab
  • Patients undergoing coronary angiography and functional assessment in the cath lab
  • Patients diagnosed as acute myocardial infarction
  • Exclusion Criteria:
  • Severe diseases of other systems may affecting the life span of patients
  • Regular return visits not available
  • 3. Atrial fibrillation
  • Inclusion Criteria:
  • PAtrial fibrillation diagnosed by electrocardiogram or holter (duration \>30 seconds)
  • Patients willing to accept long-term follow-up and regular return visits
  • Exclusion Criteria:
  • Severe diseases of other systems may affecting the life span of patients
  • New-onset atrial fibrillation during the perioperative period of major surgery
  • 4. Ventricular arrhythmias
  • Inclusion Criteria:
  • Patients diagnosed as ventricular tachycardia, ventricular premature beat
  • Patients willing to accept long-term follow-up and regular return visits
  • Exclusion Criteria:
  • Severe diseases of other systems may affecting the life span of patients
  • A transient cause of ventricular arrhythmia was determined by the doctor, and long-term follow-up was not required
  • 5. Cardiac pacemaker implantation
  • Inclusion Criteria:
  • Patients with permanent pacemaker implantations due to various causes (including bradycardia pacing, implantable cardioverter defibrillator, cardiac resynchronization therapy, leadless cardiac pacemaker, etc.)
  • Patients willing to accept long-term follow-up and regular return visits
  • Exclusion Criteria:
  • Severe diseases of other systems may affecting the life span of patients
  • 6. Structural heart disease
  • Inclusion Criteria:
  • Patients diagnosed as structural heart disease, including congenital heart disease and severe valvular disease (moderate and above valvular stenosis or incomplete closure)
  • Patients willing to accept long-term follow-up and regular return visits
  • Exclusion Criteria:
  • Severe diseases of other systems may affecting the life span of patients
  • 7. Pulmonary hypertension
  • Inclusion Criteria:
  • Patients diagnosed as pulmonary hypertension
  • Patients willing to accept long-term follow-up and regular return visits
  • Exclusion Criteria:
  • Severe diseases of other systems may affecting the life span of patients
  • 8. Heart failure
  • Inclusion Criteria:
  • Patients diagnosed as heart failure
  • Patients willing to accept long-term follow-up and regular return visits
  • Exclusion Criteria:
  • Severe diseases of other systems may affecting the life span of patients
  • 9. Rare diseases of the cardiovascular system
  • Inclusion Criteria:
  • Patients diagnosed as rare diseases in the catalog published by National Health Commission of the People's Republic of China
  • Patients willing to accept long-term follow-up and regular return visits
  • Exclusion Criteria:
  • Severe diseases of other systems may affecting the life span of patients

About Peking University First Hospital

Peking University First Hospital is a leading medical institution in China, renowned for its commitment to advancing healthcare through innovative research and clinical excellence. As a prominent sponsor of clinical trials, the hospital leverages its extensive expertise in various medical fields to conduct rigorous studies aimed at improving patient outcomes and contributing to global medical knowledge. With a multidisciplinary team of skilled researchers and clinicians, Peking University First Hospital is dedicated to the ethical conduct of clinical research, ensuring the highest standards of safety and efficacy in its trials. The institution plays a vital role in translating scientific discoveries into effective treatments, thereby enhancing the quality of care for patients both locally and worldwide.

Locations

Beijing, , China

Beijing, 北京, China

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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