Fluoride Delivery to Prevent White Spots During Orthodontic Treatment

Launched by LIVERPOOL UNIVERSITY HOSPITALS NHS FOUNDATION TRUST · Aug 6, 2021

Keywords

ClinConnect Summary

This clinical trial is looking at different ways to apply fluoride to prevent white spots on teeth during orthodontic treatment with braces. These white spots are caused by a condition called enamel demineralization, which can happen when teeth are not properly protected while wearing braces. The study is specifically aimed at children and teenagers aged 11 to 16 who are about to start their orthodontic treatment with fixed metal braces.

To be eligible for this trial, participants must be generally healthy and not have any chronic diseases that require regular medical care. They should not have had significant dental work before, and they must be willing to take part in the study. If selected, participants will receive different fluoride treatments and will help researchers understand how effective each method is in protecting teeth during orthodontic treatment. This is a great opportunity for young patients to contribute to important dental research while taking care of their oral health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Planned to receive orthodontic treatment with upper and lower fixed orthodontic appliances (braces) either alone or following a period of functional appliance treatment.
• • 11-16 years of age inclusive at the start of the fixed orthodontic appliance treatment.
• • All genders.
• • Fit and well with no chronic disease necessitating regular hospital follow-up at hospital.
• • Willing to participate
• Exclusion Criteria:
• • Significant disabilities that may affect manual dexterity;
• • Any medical complication that would contraindicate the use of the fluoride treatments or milk products;
• • Previous orthodontic treatment except Phase I functional appliance treatment;
• • From areas that have fluoridated water supply\*;
• • Full coronal coverage restorations;
• • More than 2 missing anterior teeth;
• • Showing signs of systemic illness e.g. fever, cough, loss of taste/smell;
• • Any abnormality of face, lips e.g. cleft lip and/or palate or craniofacial abnormality or soft tissues of the mouth e.g. aphthous ulcers or connective tissue disorder.