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Search / Trial NCT05010473

Cortical Contributions to Frequency Following Responses and Modulation

Launched by NORTHWESTERN UNIVERSITY · Aug 10, 2021

Trial Information

Current as of June 26, 2025

Enrolling by invitation

Keywords

ClinConnect Summary

Participants will listen to a variety of sounds while the frequency-following response (FFR) is recorded. The FFR is a sound-evoked response that mirrors the acoustic properties of the incoming acoustic signal with remarkable fidelity. The FFR is now recognized as an integrated response resulting from an interplay of early auditory subcortical and cortical systems. The cortical dynamics underlying the FFR are unclear. All stimuli will be normalized to the same root mean squared amplitude and stimulus duration and played at the same in-the-ear intensity. Thirty-two stimuli from human and ani...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age 13 years up to 25 years
  • Healthy volunteers
  • Native English speaking individuals with no exposure or experience to tonal languages
  • Native Mandarin speakers
  • Hearing sensitivity within normal limits (Puretone hearing thresholds \< 25dB from 250
  • Hz to 8000 Hz)
  • Less than six years of formal music training or experience
  • Exclusion Criteria:
  • Proficiency in languages other than English or Chinese
  • History of or current complaint of hearing loss or tinnitus
  • History of or current complaint of cognitive impairments
  • Individuals with more than 5 years of formal music experience or training
  • Complaints of impaired speech perception in noise

About Northwestern University

Northwestern University is a prestigious academic institution renowned for its commitment to advancing medical research and improving patient care through innovative clinical trials. With a robust infrastructure that supports interdisciplinary collaboration, Northwestern leverages its expertise in various fields, including medicine, engineering, and social sciences, to drive groundbreaking studies. The university is dedicated to adhering to the highest ethical standards and regulatory compliance, ensuring that all clinical trials are conducted with the utmost integrity and focus on participant safety. Through its Clinical Trials Office, Northwestern aims to translate scientific discoveries into effective therapies, ultimately enhancing health outcomes and contributing to the broader medical community.

Locations

Pittsburgh, Pennsylvania, United States

Evanston, Illinois, United States

Patients applied

0 patients applied

Trial Officials

Bharath Chandrasekaran, PhD

Principal Investigator

Northwestern University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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