The Alberta BLOOM Premature Child Study

Launched by UNIVERSITY OF CALGARY · Aug 11, 2021

Keywords

ClinConnect Summary

Premature birth (birth before 37 weeks of pregnancy) occurs in about 1 in 10 pregnancies. When infants are born prematurely their gut is not as developed. One important factor in gut health is the large community of microbes (tiny living things such as bacteria) that live on the human body called the microbiome. Recent studies have shown that premature infants are more likely to experience changes to their gut microbiome that are associated with health issues, such as asthma and allergies. However, the specific microbiome features of children born preterm and the role of their microbiome in...

Gender

ALL

Eligibility criteria

• • Inclusion Criteria
• Child Inclusion Criteria:
• • 1. Less than 8 days of age or previous participation in one of the BLOOM-PTN, BLOOM-LTFU, Pregnancy During the Pandemic or PROBIO studies;
• • 2. Born at ≤ 36 weeks + 6 days gestation (36 6/7 weeks gestational age)
• • 3. For babies recruited shortly after birth, be expected to survive more than one week;
• Mother/Parent/Legal Guardian Inclusion Criteria:
• • 1. Provide a signed and dated consent form;
• • 2. Be able to speak and understand English;
• • 3. Be 16 years of age or older;
• • 4. Be willing to comply with all study procedures and be available for the duration of the study;
• • 5. If recruited as a previous participant of the BLOOM-PTN, BLOOM-LTFU, Pregnancy During the Pandemic and/or PROBIO studies, must be willing to attend clinic visit(s) at the Alberta Children's Hospital in Calgary, Alberta at 1 and 3 years Corrected Gestational Age, or
• • 6. If recruited within 8 days of birth, must reside within the Calgary Metropolitan Region.
• • Exclusion Criteria
• Child Exclusion Criteria:
• • 1. Has major congenital or chromosomal anomalies, including any congenital gastrointestinal anomalies
• • 2. Children recruited within 8 days of birth who have a history of gastrointestinal surgery at the time of recruitment
• Mother/Parent/Legal Guardian Exclusion Criteria:
• • 1. Not the legal guardian of the child or
• • 2. In a legal guardianship dispute.