The SLEEPR Study: SLEep Effects on Post-stroke Rehabilitation

Launched by STATE UNIVERSITY OF NEW YORK - UPSTATE MEDICAL UNIVERSITY · Aug 12, 2021

Keywords

ClinConnect Summary

The SLEEPR Study is a clinical trial that investigates how sleep disorders, specifically non-obstructive sleep apnea, affect recovery in people who have had a stroke. Sleep is essential for overall health, but many stroke survivors may experience sleep issues that could impact their rehabilitation. This study aims to find out how common these sleep disorders are among stroke patients and how they influence daily activities, mobility, and overall recovery.

To participate in the study, individuals must be at least 18 years old, have been diagnosed with a stroke, and be admitted to an in-patient rehabilitation program. Participants will also need to be alert enough to understand and provide consent. However, those with certain conditions, such as obstructive sleep apnea or other serious neurological disorders, as well as pregnant women, will not be eligible. If you join the study, you can expect to help researchers better understand the relationship between sleep and recovery after a stroke, which could lead to improved care for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Diagnosis of stroke as defined by the WHO: "a rapid onset event of vascular origin reflecting a focal disturbance of cerebral function, excluding isolated impairments of higher function and persisting longer than 24 hours." Diagnosis of stroke will be confirmed by imaging or clinical diagnosis.
• • Age 18 or older.
• • Admitted to in-patient rehabilitation.
• • National Institutes of Health Stroke Scale (NIHSS) item 1a score \<2 (Level of consciousness: 0=alert, 1=not alert, but arousable by minor stimulation to obey, answer, or respond).
• • Provision of informed consent by individual or by legally authorized representative.
• Exclusion Criteria:
• • Pre-stroke or current diagnosis of OSA or other sleep-related breathing disorder.
• • Living in a nursing home or assisted living center prior to the stroke.
• • Unable to ambulate 150' independently prior to the stroke.
• • Other neurologic health condition that may impact recovery such as Parkinson Disease, Multiple Sclerosis, Traumatic Brain Injury, Alzheimer's Disease.
• • Women who are pregnant.
• • Recent hemicraniectomy or suboccipital craniectomy (i.e. those whose bone has not yet been replaced), or any other recent bone removal procedure for relief of intracranial pressure.
• • Planned discharge location \>150 miles radius from recruitment site
• • Global aphasia as defined by a NIHSS item 9 score of 3 (3= Mute, global aphasia; no usable speech or auditory comprehension).
• • Inability to understand English