Evaluating Impact of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Parathyroidectomy

Launched by UNIVERSITY OF MICHIGAN · Aug 22, 2021

Keywords

ClinConnect Summary

This clinical trial is examining whether a special tool called the Parathyroid Eye (PTeye), which uses near infrared autofluorescence (NIRAF) detection, can help surgeons identify parathyroid glands more effectively during surgery. The goal is to see if using this technology makes the surgery safer and more successful compared to relying solely on the surgeon's experience. The study will involve patients with conditions like primary hyperparathyroidism, which causes high levels of calcium in the blood, and who are scheduled for parathyroid surgery.

To participate in this trial, individuals must be diagnosed with primary hyperparathyroidism and be planning to undergo surgery. Those who have had unsuccessful parathyroid surgery in the past and require a repeat procedure may also be eligible. However, pregnant women, those needing thyroid surgery at the same time, or patients with other specific types of hyperparathyroidism will not be included. Participants can expect to be part of a study that may contribute to improving surgical outcomes for future patients, helping doctors better locate parathyroid glands during surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Primary hyperparathyroidism who will be undergoing parathyroid surgery
• • Persistent primary hyperparathyroidism after having undergone a failed prior parathyroid surgery who will be undergoing repeat parathyroid surgery
• Exclusion Criteria:
• • Pregnant women (Those patients who could potentially will receive preoperative pregnancy testing, as is standard before general anesthesia. Any patients with positive pregnancy test results will not be included in the study.)
• • Patients with concurrent parathyroid and thyroid disease that require total thyroidectomy
• • Patients with secondary or tertiary hyperparathyroidism