Athlete's Heart or Arrhythmogenic Right Ventricular Cardiomyopathy: Contribution of Exercise Cardiovascular Magnetic Resonance (CMR)

Launched by RENNES UNIVERSITY HOSPITAL · Aug 23, 2021

Keywords

ClinConnect Summary

This clinical trial is studying how exercise affects the heart, specifically looking at a condition called Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC). The researchers want to see if a special heart imaging test, called exercise cardiovascular magnetic resonance (CMR), can help doctors tell the difference between ARVC, which is a heart disease, and a condition known as "athlete's heart," which is a normal response to intense training. This is important because both conditions can cause changes to the right side of the heart, but only ARVC is harmful.

To participate in this study, you need to be at least 18 years old and fall into one of several groups: you could have ARVC but still have a functioning heart, be an endurance athlete with a dilated or normal-sized heart, or be a healthy person who doesn’t exercise much. Participants will undergo exercise tests and heart imaging to help determine how their hearts are functioning. It's also important to note that people with other heart diseases or certain medical devices may not be eligible for this study. If you're interested, the study is currently recruiting participants!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Men or women aged 18 years and older,
• • patients with confirmed ARVC, but with no major RV dysfunction (RVEF \>40%)
• • endurance athletes with dilated RV
• • endurance athletes with non-dilated RV
• • untrained healthy subjects with non-dilated RV
• * who signed a written free and informed consent:
• Exclusion Criteria:
• • Patients with other cardiovascular disease;
• • Contra-indication to CMR (in particular presence of a non-CMR compatible implantable cardiac defibrillator);
• • Patients with permanent supraventricular arrhythmia;
• • Patients unable to perform an exercise test on an ergocycle;
• • Person subject to legal protection (safeguard justice, trusteeship and guardianship) and persons deprived of liberty