Treatment of Intrabony Defects With Simvastatin and Antimicrobial Photodynamic Therapy

Launched by KAFRELSHEIKH UNIVERSITY · Aug 26, 2021

Keywords

ClinConnect Summary

This clinical trial is studying two treatments for chronic periodontitis, a serious gum disease that can cause tooth loss. The researchers want to see how well simvastatin, a medication known to help with bone healing and reduce inflammation, works alongside antimicrobial photodynamic therapy (aPDT), which uses light to help kill harmful bacteria in the mouth. The goal is to find out if using these two treatments together can improve healing in patients with intrabony defects, which are deep pockets of infection in the gums.

To participate in this study, individuals must be generally healthy, have good oral hygiene, and not have received any antibiotics or periodontal treatments for at least six months before joining. Participants will need to commit to several follow-up visits to monitor their progress. This trial is currently recruiting participants of all genders, aged between 18 and 65. If you or a loved one are interested, it might be a good opportunity to help advance treatments for gum disease while also receiving care!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients were all healthy and free from any systemic disease;
• • no history of antibiotic therapy or periodontal treatment for at least 6 months preceding the study;
• • patients were willing and able to return for multiple follow-up visits;
• • good levels of oral hygiene
• Exclusion Criteria:
• • Pregnant and lactating female patients,
• • smokers,
• • alcoholics,
• • those receiving any medication that could affect healing of soft or hard tissue