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Search / Trial NCT05035537

PGDT in Patients Undergoing Kidney Transplant

Launched by IRCCS AZIENDA OSPEDALIERO-UNIVERSITARIA DI BOLOGNA · Sep 1, 2021

Trial Information

Current as of July 23, 2025

Completed

Keywords

Perioperative Goal Directed Therapy Kidney Transplant

ClinConnect Summary

To reduce perioperative complications optimal fluid management is essential in patients undergoing kidney transplantation. Heart rate, Medium Arterial Pressure (MAP), Central Venous Pressure (CVP), and urine output have been proposed in the literature to guide perioperative fluid therapy. These criteria are routinely applied in clinical practice; however these criteria have shown low sensitivity and poor predictive of postoperative complication, especially if used alone. The traditional approach in renal transplantation is the volume infusion guided whit CVP to the point of no further fluid...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • age \> 18 years,
  • first single- or dual-kidney transplant from a deceased donor,
  • absence of atrial fibrillation or other severe arrythmia,
  • ASA (American Society of Anesthesiologists) class III-IV,
  • presence of written expression of consent.
  • Exclusion Criteria:
  • patients receiving a retransplant,
  • patients receiving a combined liver-kidney transplant,
  • patients receiving a transplant from a living donor .

About Irccs Azienda Ospedaliero Universitaria Di Bologna

IRCCS Azienda Ospedaliero-Universitaria di Bologna is a prestigious research and healthcare institution in Italy, renowned for its commitment to advancing medical science and patient care through innovative clinical research. As an IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), it integrates clinical practice with scientific research, facilitating the translation of laboratory findings into effective treatment strategies. The institution fosters a multidisciplinary approach, collaborating with various experts to conduct high-quality clinical trials aimed at improving health outcomes across a wide range of medical fields. With a strong emphasis on ethical standards and patient welfare, IRCCS Azienda Ospedaliero-Universitaria di Bologna plays a vital role in shaping the future of medicine through rigorous scientific inquiry and patient-centered care.

Locations

Ancona, , Italy

Torino, , Italy

Patients applied

0 patients applied

Trial Officials

Antonio Siniscalchi, MD

Principal Investigator

IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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