Ethanolic Extract of Sapindus Mukorrossi as Final Endodontic Irrigant.
Launched by DOW UNIVERSITY OF HEALTH SCIENCES · Aug 31, 2021
Trial Information
Current as of July 24, 2025
Completed
Keywords
ClinConnect Summary
Preparation of ethanolic extract of S.mukorossi:
The desiccated fruit of Sapindus mukorossi will be used for the formulation of an experimental root canal irrigant. The dry pericarps of s. mukorossi (≈ 1.0 kg) which is present around the seed nut, will be separated with a sharp blade. These pericarps will be blended to produce fine particles in a sterilized home blender (Enviro 3 in 1 juicer blender ENJ301). The resultant 10gram powder will be soaked in 100ml of absolute ethanol (99%) for 24hours at normal room temperature. This solvent will be filtered and removed with help of a rotary ev...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Extracted single rooted teeth with mature apices. (carious/ non carious)
- • Teeth extracted for orthodontic and periodontal purpose.
- • Patient age between 18 to 40 years.
- Exclusion Criteria:
- • Intracanal calcification. (will be assessed from pre-operative radiograph before extraction)
- • Root dilacerations.
- • Root caries, fracture or cracked.
- • Root resorption.
- • Previously treated or initiated root canal treatment.
About Dow University Of Health Sciences
Dow University of Health Sciences (DUHS) is a premier educational and research institution based in Karachi, Pakistan, dedicated to advancing healthcare through innovative research and clinical excellence. As a clinical trial sponsor, DUHS integrates cutting-edge scientific inquiry with practical applications, fostering a collaborative environment that promotes the development of new treatments and therapies. The institution is committed to upholding the highest ethical standards in research, ensuring participant safety, and contributing to the global body of medical knowledge. With a focus on interdisciplinary collaboration and community health impact, DUHS plays a pivotal role in enhancing the quality of healthcare both locally and internationally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Karachi, Sindh, Pakistan
Patients applied
Trial Officials
Araib AT Tahir, BDS
Principal Investigator
dow university
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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