Effects of Pulmonary Diseases and Their Treatment on Cardiac Function

Launched by AYHAM DAHER · Sep 10, 2021

Keywords

ClinConnect Summary

This clinical trial is studying how lung diseases, like COPD (chronic obstructive pulmonary disease), bronchial asthma, and idiopathic pulmonary fibrosis, affect heart function. Researchers want to understand how treatments for these lung diseases may also influence the heart. They will use advanced imaging techniques called cardiac MRI to look at heart function and structure in patients with these conditions, both when they are first diagnosed and after starting treatment. The goal is to identify any heart problems early on and see how treatment helps over time.

To be eligible for the trial, participants must be over 18 years old and have a chronic lung disease that requires treatment. It's important that they can give informed consent, meaning they understand what the study involves. Participants will undergo cardiac MRI and echocardiography (another type of heart imaging) to assess their heart health. They can expect to be closely monitored for 3 to 6 months after they start their treatment to see how their heart function changes. This study is crucial for improving our understanding of the connection between lung and heart health, which can help doctors provide better care for patients with these diseases.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with chronic lung disease requiring treatment (COPD, asthma, or pulmonary fibrosis).
• • Age \> 18 years
• • Informed consent to participate in the study will sign
• Exclusion Criteria:
• • Individuals who are not fully capable of giving consent and understanding the nature, significance and scope of the study.
• • Patients with contraindications to MRI examination (eg, pacemaker, severe claustrophobia) or to contrast medium use (severe renal insufficiency or glomerular filtration rate \<30 ml/min, known gadolinium contrast medium allergy)
• • Patients with atrial fibrillation or other significant cardiac arrhythmias that interfere with cardiac MRI
• • Pregnancy and lactation