The Effect of Leukocyte and Platelet-rich Fibrin With Antimicrobial Photodynamic Therapy in Aggressive Periodontitis

Launched by KAFRELSHEIKH UNIVERSITY · Sep 5, 2021

Keywords

ClinConnect Summary

This clinical trial is studying how two treatments can help people with aggressive periodontitis, a severe form of gum disease. The treatments being tested are called antimicrobial photodynamic therapy (aPDT) and leukocyte and platelet-rich fibrin (L-PRF). The aPDT uses light and special agents to kill harmful bacteria in the gums, while L-PRF, made from a patient’s own blood, helps heal and regenerate gum tissue. The goal is to see how these treatments work together and if they can improve the health of gums in patients with this condition.

To participate in the trial, individuals must be healthy, non-smokers, and not have had any periodontal treatments or taken certain medications in the past six months. They should also be able to manage their oral hygiene without any physical limitations. Participants will receive either one of the treatments or a combination of both and will be monitored for their progress. This study may provide valuable insights into better ways to treat aggressive periodontitis and improve dental health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • systemically healthy
• • non- smoker,
• • not received any periodontal treatment within the last 6 months,
• • no antibiotics, anti- inflammatory drugs or any other medication taken within the last 6 months
• Exclusion Criteria:
• • any systemic disease that might influence the prognosis of periodontal disease and outcome of the treatment,
• • any medical condition that required antibiotic prophylaxis before the treatment,
• • smoking,
• • pregnancy and lactation,
• • ingestion of antibiotics, anti-inflammatory drugs or any other medication during the study period,
• • any physical limitations or restrictions that might preclude normal oral hygiene procedures.