Pulmonary Aspergillosis in Tuberculosis Patients

Launched by RESEARCH INSTITUTE OF EPIDEMIOLOGY, MICROBIOLOGY AND INFECTIOUS DISEASES, UZBEKISTAN · Sep 6, 2021

Keywords

ClinConnect Summary

This clinical trial is focused on understanding how common a fungal infection called aspergillosis is among patients with pulmonary tuberculosis (PTB), which is a serious lung condition. The researchers want to see how often aspergillosis occurs in patients who test positive and negative for the bacteria that cause tuberculosis (Koch's bacillus). They also aim to check if the aspergillus fungi are resistant to antifungal treatments in Central Asia. This information is important because diagnosing aspergillosis in PTB patients can be challenging, especially in places where medical resources are limited.

To participate in this trial, individuals must be diagnosed with pulmonary tuberculosis, either with a positive or negative smear test. However, those who have weakened immune systems due to certain conditions, like cancer treatment or organ transplants, or who are HIV positive, cannot join. Participants in this study will likely undergo various tests to help doctors better understand the connection between tuberculosis and aspergillosis, which could lead to better treatment options for patients in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Pulmonary tuberculosis patients (smear-positive)
• • Pulmonary tuberculosis patients (smear - negative)
• Exclusion Criteria:
• • neutropenia
• • severe immunosuppression caused by cancer chemotherapy
• • hematopoietic stem cell or solid organ transplantation
• • HIV infected individuals