Assessment in Patients With Essential Trigeminal Neuralgia of Nerve Involvement by MRI in DTI and Functional Connectivity in "Resting State"
Launched by FONDATION OPHTALMOLOGIQUE ADOLPHE DE ROTHSCHILD · Sep 20, 2021
Trial Information
Current as of July 21, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a condition called essential trigeminal neuralgia, which is a common type of facial pain. The goal is to find better ways to understand how the trigeminal nerve is affected by looking at images of the brain using advanced MRI techniques. The researchers want to see if adding special types of MRI scans can help doctors identify the cause of the pain more accurately, guide surgical treatment options, and predict how well patients might recover after surgery.
To participate in this trial, you need to be an adult (18 years or older) experiencing one-sided trigeminal neuralgia and being evaluated for potential surgery. Unfortunately, if you have certain neurological conditions, have had previous surgery for this issue, cannot undergo an MRI for health reasons, or are pregnant or nursing, you won't be eligible. If you join the study, you can expect a thorough assessment using different MRI techniques to help in understanding your condition better and making informed treatment decisions.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Adult patients (18 years and over);
- • Supported in the neurosurgery department or at the assessment and treatment center for pain for unilateral essential trigeminal neuralgia with search for vasculo-nervous conflict;
- Exclusion Criteria:
- • Patient with neurodegenerative or inflammatory neurological pathology;
- • Patient who has already been operated on for a DMV;
- • Absolute contraindication to MRI
- • Patient benefiting from a legal protection measure; with impaired judgment skills or unable to receive information;
- • Pregnant or breastfeeding women
About Fondation Ophtalmologique Adolphe De Rothschild
The Fondation Ophtalmologique Adolphe de Rothschild is a leading French institution dedicated to advancing ophthalmic research and patient care. Renowned for its commitment to innovation in eye health, the foundation conducts cutting-edge clinical trials aimed at improving treatments for various ocular conditions. With a multidisciplinary team of experts, the foundation collaborates with academic and industry partners to enhance understanding of eye diseases and develop novel therapeutic solutions, ultimately striving to improve patient outcomes and quality of life in ophthalmology.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Paris, , France
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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