EPLBD With Limited EST vs. EPLBD for Choledocholithiasis

Launched by JIANFENG YANG · Sep 20, 2021

Keywords

ClinConnect Summary

This clinical trial is examining two different treatment approaches for people with large bile duct stones, also known as choledocholithiasis. The goal is to compare the effectiveness and safety of a new method that combines limited endoscopic sphincterotomy (a procedure to cut the muscle around the bile duct) with endoscopic papillary balloon dilation, against a more traditional method using a larger balloon for dilation. This study is particularly interested in patients with stones that are 10 mm or larger, as these larger stones can be more challenging to remove.

To be eligible for this trial, participants should be adults aged 65 to 74 and must have large bile duct stones. However, certain individuals cannot participate, including pregnant women, those who have had specific prior procedures, or those with certain medical conditions like bleeding disorders or severe infections. If you choose to participate, you'll be helping researchers understand which treatment option works better for removing these larger stones safely. The trial is currently recruiting participants, so it's an excellent opportunity for those who qualify and are looking for treatment options.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • large bile duct stones (≥10 mm)
• Exclusion Criteria:
• • pregnancy
• • refusal of written informed consent
• • Patients with benign or malignant biliary stricture
• • Contraindications to ERCP exist
• • Complicated with acute pancreatitis or acute cholangitis
• • Coagulation dysfunction，thrombocytopenia
• • prior EST or EPBD
• • Patients after gastrointestinal reconstruction