LCI-PED-NOS-EXER-001: Exercise in Pediatric Oncology Patients

Launched by WAKE FOREST UNIVERSITY HEALTH SCIENCES · Sep 23, 2021

Keywords

ClinConnect Summary

This clinical trial, called LCI-PED-NOS-EXER-001, is looking at how exercise can help children and young adults, aged 2 to 25, who have recently been diagnosed with cancer. The study aims to find out if joining a structured exercise program while they are undergoing treatment can improve their physical and emotional well-being. Researchers believe that exercise may help these young patients feel better both physically and mentally during their cancer journey.

To participate, individuals must be newly diagnosed with cancer and ready to start chemotherapy or other treatments. They need to be able to understand instructions in English or Spanish and commit to the study for at least three months. However, there are some people who cannot join, such as those with certain heart issues or recent surgeries that limit movement. If eligible, participants can expect to take part in specific exercise sessions designed for their needs, which could make a positive difference in their treatment experience.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Ages 2-25 at time of consent
• • 2. Subject has newly diagnosed cancer per Investigator, and is planning to undergo chemotherapy for treatment of malignancy for at least 3 full cycles
• • 3. Ability of subject (and/or parent/guardian) to read and understand the English or Spanish language
• • 4. As determined and documented by the enrolling investigator, ability of the subject to understand and comply with study procedures for the entire length of the study
• • 5. Subject has newly diagnosed cancer per Investigator and is planning to undergo chemotherapy, immunotherapy, or other systemically delivered for treatment of malignancy. Subjects are allowed to be enrolled up to 5 days after initiating cancer treatment.
• • 6. Receiving oncologic care at Levine Children's Cancer and Blood Disorders Clinic.
• • 7. Subject is anticipated to receive at least 3 full cycles90 days of chemotherapy or other systemic cancer treatment.
• • 8. Not participating in another clinical trial that precludes participating in additional nondrug clinical trials.
• Exclusion Criteria:
• • 1. Known cardiac dysfunction that, in the opinion of the investigator, would be unsafe for the child to participate in the exercise program
• • 2. Any other uncontrolled intercurrent illness/medical condition or psychiatric illness/social situations that would limit compliance with study requirements or would be considered unsafe for the child to participate as determined by the Investigator.
• • 3. Recent (within 4 weeks of enrollment) or planned surgery that will result in prolonged limited mobility not amendable to exercise modifications per investigator discretion
• • 4. Primary CNS Tumor
• • 5. Osteosarcoma