Minipuberty in Infants Born With Potential Hypogonadism Hypogonadotrope

Launched by CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS · Sep 17, 2021

Keywords

ClinConnect Summary

This clinical trial is studying hormone levels in infants who have certain conditions related to their sexual development, specifically disorders of sex development (DSD) and congenital hypogonadism hypogonadotrope (CHH). These conditions can affect how the external genital organs appear in newborns. The researchers aim to understand how hormones behave during a specific period shortly after birth, known as minipuberty, in infants with DSD or those born to parents with CHH, and compare their findings to those of healthy infants.

To participate in this study, infants must either show signs of DSD or be born to parents with CHH. However, infants who were born prematurely (before 35 weeks) or have certain severe conditions like high scrotal cryptorchidism (where the testicles have not descended properly) cannot take part. Families interested in the study can expect to have their child's hormone levels monitored during this early stage of life, which could provide valuable insights into these conditions. The trial is currently looking for participants, and all infants, regardless of gender, are welcome to join.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • infants born with symptoms of DSD
• • infants born from parents with CHH
• Exclusion Criteria:
• • premature \< 35 weeks of gestation
• • male infants with high scrotal cryptorchidism