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Search / Trial NCT05065151

Understanding Motivation in Parkinson's Patients Through Neurophysiology

Launched by UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · Sep 29, 2021

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Parkinson's Medtronic Percept Dbs Deep Brain Stimulation Parkinson's Disease Parkinson Disease Pd Reward Based Decision Making Task

ClinConnect Summary

This clinical trial is focused on understanding how motivation works in people with Parkinson's Disease, especially those who have a special device called the Medtronic Percept PC Deep Brain Stimulation (DBS) device implanted in their brains. The researchers want to learn how this device can help us understand how Parkinson's patients make decisions based on their motivations. This could lead to better treatments and support for individuals living with Parkinson's.

If you or someone you know has Parkinson's Disease and has the Medtronic Percept PC DBS device implanted, you may be eligible to participate in this study. However, participants should not have severe cognitive impairments, which means they should be able to think and understand information clearly. Those who join the trial can expect to take part in activities that help researchers learn more about their motivations and decision-making processes. This study is currently recruiting participants aged 65 to 74, and both men and women are welcome to join.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Has Parkinson's Disease or Dystonia
  • Has Medtronic Percept or RC+S DBS device implanted in either GPI or STN
  • Has DBS device implanted either bilaterally or unilaterally
  • Male or female
  • More than 1 month post-DBS surgery
  • Exclusion Criteria:
  • Severe cognitive impairments
  • Has MOCA score below 20
  • Pregnancy
  • Age less than 18 years old

About University Of California, San Francisco

The University of California, San Francisco (UCSF) is a leading academic institution renowned for its commitment to advancing healthcare through innovative research and clinical trials. With a focus on translating scientific discoveries into effective therapies, UCSF collaborates with a diverse array of stakeholders, including healthcare professionals, industry partners, and patient communities. The university's research programs emphasize interdisciplinary approaches and leverage cutting-edge technology to address complex medical challenges. As a sponsor of clinical trials, UCSF is dedicated to maintaining the highest standards of ethical conduct and scientific rigor, ensuring the safety and well-being of participants while contributing to the broader medical knowledge base.

Locations

San Francisco, California, United States

San Francisco, California, United States

Patients applied

0 patients applied

Trial Officials

Simon J Little, MBBS, PhD

Principal Investigator

University of California, San Francisco

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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