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Search / Trial NCT05072236

Effects of Adding Different Drugs for Preventing Cough Induced by Bronchoscopic Spraying of Local Anesthetics

Launched by NATIONAL TAIWAN UNIVERSITY HOSPITAL · Oct 5, 2021

Trial Information

Current as of September 09, 2025

Recruiting

Keywords

Cough Desaturation Ventilation Bronchoscopic Interventions

ClinConnect Summary

This clinical trial is studying how different medications can help prevent coughing during a specific medical procedure called bronchoscopy, which is used to examine the lungs and treat lung tumors. Coughing during this procedure can cause problems, such as making it harder for doctors to see clearly or affecting the patient's breathing. The trial will compare the effects of two intravenous drugs, lidocaine and alfentanil, with a placebo (normal saline) to see which option works best at reducing cough during the bronchoscopic spraying of local anesthetics.

To participate in this trial, individuals must be adults who are scheduled to undergo bronchoscopic procedures for lung tumors while receiving intravenous anesthesia. The trial is currently recruiting participants and welcomes all genders. Those who join can expect to receive one of the study drugs shortly before the procedure, and their responses, including cough intensity and breathing levels, will be monitored and recorded. This research aims to improve patient comfort and the overall success of bronchoscopic interventions.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • patients planned to receive bronchoscopic interventions for lung tumors with intravenous anesthesia.
  • Exclusion Criteria:
  • conventional bronchoscopy without interventions such as EBUS, tracheal tumore excision

About National Taiwan University Hospital

National Taiwan University Hospital (NTUH) is a leading medical institution renowned for its commitment to advancing healthcare through innovative research and clinical trials. As a pioneer in medical education and patient care in Taiwan, NTUH integrates cutting-edge technology with comprehensive clinical expertise to facilitate groundbreaking studies across various medical fields. The hospital’s dedicated research team collaborates with local and international partners to enhance the understanding of diseases and improve treatment outcomes. By prioritizing patient safety and ethical standards, NTUH strives to contribute to the global medical community and foster advancements in healthcare practices.

Locations

Taipei, Taiwan

Patients applied

0 patients applied

Trial Officials

Yajung Cheng

Study Chair

National Taiwan University Hospital, Cancer Center

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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