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Search / Trial NCT05073471

Music and Brain Stimulation for Upper Extremity Performance in Patients With Corticobasal Syndrome

Launched by JOHNS HOPKINS UNIVERSITY · Sep 29, 2021

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Corticobasal Syndrome (Cbs) Neurologic Music Therapy (Nmt) Patterned Sensory Enhancement (Pse) Transcranial Direct Current Stimulation (T Dcs) T Dcs/Eeg Upper Extremity Performance

ClinConnect Summary

This clinical trial is exploring how music and a type of brain stimulation might help improve movement and function in the arms of patients with Corticobasal Syndrome (CBS), a condition that affects movement. The study will involve 20 participants who will be divided into two groups: one group will listen to music designed to enhance movement, while the other group will listen to the same music and also receive non-invasive brain stimulation. Both groups will participate in 30-minute sessions twice a week for three weeks.

To be eligible for the study, participants must be between the ages of 18 and 89, right-handed, and diagnosed with CBS. However, individuals with certain medical conditions, such as skin issues, a history of migraines, or those who have had a serious head injury, will not be able to participate. Throughout the study, participants will be asked to share their experiences, and various tests will be conducted to measure improvements in arm function, mood, and quality of life. This research aims to find effective, low-cost rehabilitation options for CBS patients in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients with CBS
  • Age range 18-89
  • Right-handed
  • Exclusion Criteria:
  • A history of migraines
  • Have a scalp or skin condition (e.g., psoriasis or eczema)
  • Have any metallic implants, including intracranial electrodes, surgical clips, shrapnel or a pacemaker
  • Have had a head injury resulting in a loss of consciousness that has required further investigation
  • Have diagnosed psychological or neurological disorders
  • Have had a seizure
  • Have had adverse effects to previous tDCS or other brain stimulation techniques (e.g., TMS)
  • Pregnancy
  • Inability or unwillingness to follow directions for study procedures

About Johns Hopkins University

Johns Hopkins University, a prestigious research institution located in Baltimore, Maryland, is renowned for its commitment to advancing medical science and public health through innovative clinical trials. With a rich history of groundbreaking research and a multidisciplinary approach, the university's clinical trial initiatives focus on translating scientific discoveries into effective treatments and interventions. Leveraging state-of-the-art facilities and a collaborative network of experts, Johns Hopkins University conducts rigorous clinical studies that aim to improve patient outcomes and address critical health challenges. Its dedication to ethical standards and participant safety underscores its role as a leader in clinical research.

Locations

Baltimore, Maryland, United States

Patients applied

0 patients applied

Trial Officials

Alexander Pantelyat, MD

Principal Investigator

Department of Neurology, Johns Hopkins School of Medicine

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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