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Search / Trial NCT05075252

Re-assessment of Appendicitis Evaluation During Laparoscopic Appendectomy, Peritoneal Irrigation During Laparoscopic Appendectomy Does the Grade of Contamination Matter?

Launched by NIGUARDA HOSPITAL · Sep 29, 2021

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Laparoscopy Appendicitis Appendectomy Lavage Suction Abscess

ClinConnect Summary

This clinical trial is studying the effects of a procedure called laparoscopic lavage during laparoscopic appendectomy, which is surgery to remove the appendix. Researchers want to find out if using this washing technique impacts the chances of developing complications, like abscesses (pockets of infection) after surgery, especially in patients with different levels of infection and severity of appendicitis. The goal is to understand whether this technique should be used based on how severe the condition is and how contaminated the abdominal area is during the operation.

To be eligible to participate, patients must be between 18 and 69 years old and diagnosed with acute appendicitis that requires laparoscopic surgery. Patients who have had previous surgeries for appendicitis, other abdominal infections, or certain health conditions, like immune system issues, cannot participate. Those who join the trial will contribute to important research that could help improve surgical practices and outcomes for future patients with appendicitis.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients between 18 and 69 years old
  • Surgical laparoscopic approach for AA
  • Intra-operative and histological diagnosis of AA
  • Exclusion Criteria:
  • Patients \< 18 years old or \> 69 years old
  • Previous appendectomy
  • Previous appendicitis treated conservatively
  • Open approach for surgery or intra-operative conversion
  • Co-existence of other intra-abdominal infections (IAI)
  • Patients with immunodeficiency
  • Patients treated with steroid, immunosuppressant, or CHT within previous 6 months

About Niguarda Hospital

Niguarda Hospital, located in Milan, Italy, is a leading healthcare institution renowned for its commitment to innovative medical research and high-quality patient care. As a prominent clinical trial sponsor, Niguarda Hospital actively engages in multidisciplinary studies aimed at advancing medical knowledge and improving therapeutic outcomes across various specialties. The hospital's state-of-the-art facilities and a team of experienced researchers and clinicians foster a collaborative environment that prioritizes ethical standards and patient safety. Niguarda Hospital is dedicated to translating research findings into clinical practice, ultimately enhancing the standard of care for patients both locally and globally.

Locations

Milano, , Italy

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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