The Prevalence Survey of ALDH Gene Family in Patients With Peripheral Arterial Occlusive Disease or Acute Coronary Syndrome

Launched by CHIMEI MEDICAL CENTER · Oct 1, 2021

Keywords

ClinConnect Summary

This clinical trial is looking at a specific gene called ALDH2 and how its deficiency might affect patients with two serious heart conditions: Peripheral Arterial Occlusive Disease (PAOD) and Acute Coronary Syndrome (ACS). The ALDH2 gene helps break down substances in the body that can be harmful, especially after consuming alcohol. People who have a deficiency in this gene may experience certain health issues, including a higher risk of heart problems and cancer. The study aims to better understand how common this gene deficiency is among people with PAOD and ACS, particularly since it is more prevalent in Asian populations.

To participate in this study, you need to be at least 20 years old and have a confirmed diagnosis of either PAOD (which can cause leg pain when walking) or ACS (a condition related to heart attacks). If you decide to join, you will help researchers gather important information about the relationship between the ALDH2 gene and these heart conditions. Your participation could contribute to better understanding and treatment options for people facing similar health challenges.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age≧20 y/o
• • 2. Using ankle-brachial index (ABI)\< 0.9, angiography, vascular duplex, CAT scan or cardiologists'impression to confirm the diagnosis of PAOD
• • 3. Clinical presentation of claudication
• • 4. diagnosis of ACS
• Exclusion Criteria:
• • If the patient refuses to be included in this study