Biomarker of Diabetic Retinopathy

Launched by INDIANA UNIVERSITY · Oct 12, 2021

Keywords

ClinConnect Summary

This clinical trial is studying diabetic retinopathy (DR), a condition that affects the eyes of people with diabetes. DR occurs when the blood vessels in the retina, the part of the eye that helps us see, become damaged. This can lead to vision problems because the retina doesn't get enough oxygen and nutrients. The goal of this study is to find a specific marker in the blood that can indicate the health of these retinal blood vessels, helping doctors understand and potentially treat DR better.

To participate in this trial, you need to be between 65 and 74 years old and have type 2 diabetes. You should also be able to go through imaging tests and have no history of certain eye treatments or other serious health issues, like cancer or infections. If you join the study, you can expect to undergo some tests and imaging to help researchers gather important information. This study is currently looking for participants, and your involvement could contribute to better understanding and management of diabetic retinopathy in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Ability to cooperate with imaging procedures.
• • Health status: established type 2 diabetes
• • No history of panretinal photocoagulation (PRP)
• • No history of treatment with intravitreal agents for past 12 months
• Exclusion Criteria:
• • Previous or current malignancy
• • Acute or chronic infection (HIV, hepatitis B or C, tuberculosis)
• • Cerebral vascular accident or cerebral vascular procedure
• • Current pregnancy
• • History of organ transplantation
• • Presence of a graft (to avoid any effect of the graft)
• • History of previous vitrectomy
• • Subjects with a history of age-related macular degeneration age-related macular degeneration (AMD), glaucoma, uveitis, and branched or central vein occlusion.