UPLYFT For Lymphoma Survivors
Launched by DANA-FARBER CANCER INSTITUTE · Oct 5, 2021
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
The UPLYFT study is designed to help lymphoma survivors manage their concerns about cancer recurrence and improve their overall quality of life. The program, called UPLYFT (Understand and Prevail: Lymphoma Fear of Recurrence Therapy), offers useful information and tools to support individuals who have completed their initial lymphoma treatment. Researchers are currently looking for participants aged 18 and older who are in complete remission from lymphoma (including non-Hodgkin lymphoma and Hodgkin lymphoma) and have been out of treatment for at least three months but no longer than 24 months.
Eligible participants will take part in a supportive intervention that focuses on addressing fears related to the return of cancer. To join, participants need access to a computer for online meetings. It's important to note that individuals with other serious mental health conditions or concurrent cancers are not eligible for this study. This trial aims to provide valuable insights that could help many lymphoma survivors feel more secure and empowered in their recovery journey.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- Lymphoma Survivors Phase 1 and 2:
- • Diagnosis of lymphoma (indolent non-Hodgkin lymphoma, aggressive non-Hodgkin lymphoma, or classic Hodgkin lymphoma)
- • Age ≥ 18 years
- • Interval of 3 months to 24 months from completion of first-line treatment
- • In complete remission after first line of treatment
- • Clinically significant FCR (score of ≥ 16 on the validated FCR Inventory-Severity Subscale \[FCRI-SS).
- • Access to computer (for videoconferencing)
- Lymphoma clinicians and mental health clinicians Phase 1:
- • Lymphoma clinicians ≥ 1 year from oncology fellowship completion OR mental health clinicians (psychologists, social workers, psychiatrists) ≥ 1 year from completion of clinical training.
- • Longitudinal clinical care for patients with lymphoma by oncologists OR provision of care for patients with cancer by mental health clinicians
- Exclusion Criteria:
- Lymphoma Survivors Phase 1:
- • Age \< 18 years
- • Concurrent other malignancy
- • Patients with uncontrolled/untreated psychotic disorders or untreated bipolar and borderline personality disorder (as ascertained from medical record screen).
- Lymphoma Survivors Phase 2:
- • Age \< 18 years
- • Concurrent other malignancy
- • Patients with uncontrolled/untreated psychotic disorders or untreated bipolar and borderline personality disorders (as ascertained from medical record screen).
- * Our study will exclude members of the following special populations:
- • Adults unable to consent
- • Individuals who are not yet adults (infants, children, teenagers)
- • Pregnant women
- • Prisoners
About Dana Farber Cancer Institute
The Dana-Farber Cancer Institute is a premier cancer research and treatment institution located in Boston, Massachusetts. Renowned for its commitment to advancing cancer care through innovative research, the institute integrates cutting-edge clinical trials with a multidisciplinary approach to patient care. With a focus on translating scientific discoveries into effective therapies, Dana-Farber collaborates with a network of leading researchers and healthcare professionals to improve outcomes for patients with cancer. The institute’s dedication to education, advocacy, and community engagement further underscores its mission to eradicate cancer and enhance the quality of life for those affected by the disease.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Boston, Massachusetts, United States
Patients applied
Trial Officials
Oreofe O Odejide, MD, PhD
Principal Investigator
Oreofe_Odejide@dfci.harvard.edu
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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