Luteal Phase Support in IUI MOH Treatment Luteal Phase Support in IUI MOH Treatment

Launched by UMC UTRECHT · Oct 12, 2021

Keywords

ClinConnect Summary

The LUMO study is a clinical trial designed to investigate how luteal phase support—additional treatment to help support the second half of a woman’s menstrual cycle—can improve the chances of pregnancy for women undergoing a specific fertility treatment called IUI with Mild Ovarian HyperStimulation (MOH). This treatment aims to help couples who have been diagnosed with unexplained infertility, meaning there isn't a clear reason why they are having trouble getting pregnant.

To be eligible for this study, participants need to be women over 18 years old with regular menstrual cycles and a specific sperm count from their partner. The trial is looking for couples who are starting IUI with MOH and plan to continue this treatment for at least six months. During the study, women may receive additional support during the luteal phase of their cycle, and researchers will monitor the outcomes to see if this helps improve their chances of pregnancy. The study is currently not recruiting participants, but if you or someone you know is considering fertility treatment, this trial could be an important opportunity in the future.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Couples starting IUI with Mild Ovarian HyperStimulation (MOH), with the intend to receive this treatment for at least six months.
• • Diagnosis of unexplained (primary or secondary) infertility
• • Hunault \<30% (or \>30%, after an expectant management period of at least 6 additional months).
• • Females aged \>18 years with regular menstrual cycle.
• • Total mobile sperm count (VCM) \>10 million.
• Exclusion cirteria:
• • Cycle irregularities
• • Male factor infertility